This purpose of this project was to update existing standards previously developed by C&I Engineering, and develop new standards for Powder Sampling Rooms and Powder Silo Rooms. The nutritional industry is a very special business. There are many aspects of the facilities used to manufacture these products which directly affect product quality and safety. All C&I disciplines were involved in development of the standards. The standards have been distributed worldwide, and are being actively used by the respective client’s Nutritional Powder plants in USA, Europe, Asia, and Latin America. The parent company has reviewed the Design Guidelines and installed them on their Engineering Design Standards website for reference use by all of their pharmaceutical facilities. The Global Design Standards were developed to ensure a consistent method of design for all of the client’s nutritional worldwide facilities as related to construction of facilities, processing areas, and equipment support systems. Specific design guidelines were developed for the following: Hygiene Definitions and zone maps, Plant layout considerations of adjacency and employee/material flow , Vitamin Weigh Room, Dry powder Blending/Milling, Powder Filling, Product Rework, Spray Drying, Fluid Bed Processing, Special Hot rooms, Powder Dumping, Wet Processing, Bag Stripping, Ante Rooms, Packaging, Warehouse and special Material Storage, Mechanical/Utility maintenance Rooms, CIP/COP Rooms, Powder Sampling Rooms, Powder Silo rooms, Microbiological Laboratory, Sample Prep Laboratory, Physical Property Laboratory, Analytical laboratory. The Design Guideline for each Standard encompassed the following topics: Building/ Architectural, Electrical Systems, Mechanical Systems, Conditioned Air Systems, Process Equipment.